Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation

Cardiac hypertrophy, an adaptive process that responds to increased wall stress, is characterized by the enlargement of cardiomyocytes and structural remodeling. It is stimulated by various growth signals, of which the mTORC1 pathway is a well-recognized source. Here, we show that loss of Flcn, a no...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hasumi, Yukiko, Baba, Masaya, Hasumi, Hisashi, Huang, Ying, Lang, Martin, Reindorf, Rachel, Oh, Hyoung-bin, Sciarretta, Sebastiano, Nagashima, Kunio, Haines, Diana C., Schneider, Michael D., Adelstein, Robert S., Schmidt, Laura S., Sadoshima, Junichi, Marston Linehan, W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189904/
https://ncbi.nlm.nih.gov/pubmed/24908670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu286
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