Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation

Cardiac hypertrophy, an adaptive process that responds to increased wall stress, is characterized by the enlargement of cardiomyocytes and structural remodeling. It is stimulated by various growth signals, of which the mTORC1 pathway is a well-recognized source. Here, we show that loss of Flcn, a no...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hasumi, Yukiko, Baba, Masaya, Hasumi, Hisashi, Huang, Ying, Lang, Martin, Reindorf, Rachel, Oh, Hyoung-bin, Sciarretta, Sebastiano, Nagashima, Kunio, Haines, Diana C., Schneider, Michael D., Adelstein, Robert S., Schmidt, Laura S., Sadoshima, Junichi, Marston Linehan, W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189904/
https://ncbi.nlm.nih.gov/pubmed/24908670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu286
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