Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. Recent studies have revealed potential functions for Flcn in kidney; however, kidney-specific functions for Fnip1 and Fnip2 are unknown. Here we demonstrate th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hasumi, Hisashi, Baba, Masaya, Hasumi, Yukiko, Lang, Martin, Huang, Ying, Oh, HyoungBin F., Matsuo, Masayuki, Merino, Maria J., Yao, Masahiro, Ito, Yusuke, Furuya, Mitsuko, Iribe, Yasuhiro, Kodama, Tatsuhiko, Southon, Eileen, Tessarollo, Lino, Nagashima, Kunio, Haines, Diana C., Linehan, W. Marston, Schmidt, Laura S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386336/
https://ncbi.nlm.nih.gov/pubmed/25775561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419502112
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