Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. Recent studies have revealed potential functions for Flcn in kidney; however, kidney-specific functions for Fnip1 and Fnip2 are unknown. Here we demonstrate th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hasumi, Hisashi, Baba, Masaya, Hasumi, Yukiko, Lang, Martin, Huang, Ying, Oh, HyoungBin F., Matsuo, Masayuki, Merino, Maria J., Yao, Masahiro, Ito, Yusuke, Furuya, Mitsuko, Iribe, Yasuhiro, Kodama, Tatsuhiko, Southon, Eileen, Tessarollo, Lino, Nagashima, Kunio, Haines, Diana C., Linehan, W. Marston, Schmidt, Laura S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386336/
https://ncbi.nlm.nih.gov/pubmed/25775561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419502112
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