Phospholipase D Regulates Myogenic Differentiation through the Activation of Both mTORC1 and mTORC2 Complexes

How phospholipase D (PLD) is involved in myogenesis remains unclear. At the onset of myogenic differentiation of L6 cells induced by the PLD agonist vasopressin in the absence of serum, mTORC1 complex was rapidly activated, as reflected by phosphorylation of S6 kinase1 (S6K1). Both the long (p85) an...

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Bibliografski detalji
Glavni autori: Jaafar, Rami, Zeiller, Caroline, Pirola, Luciano, Di Grazia, Antonio, Naro, Fabio, Vidal, Hubert, Lefai, Etienne, Némoz, Georges
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Signal Transduction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121405/
https://ncbi.nlm.nih.gov/pubmed/21525000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203885
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