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Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)

The mammalian target of rapamycin (mTOR) is a critical sensor of nutritional sufficiency. Although much is known about the regulation of mTOR in response to growth factors, much less is known about the regulation of mTOR in response to nutrients. Amino acids have no impact on the signals that regula...

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Detalhes bibliográficos
Main Authors: Xu, Limei, Salloum, Darin, Medlin, Phil S., Saqcena, Mahesh, Yellen, Paige, Perrella, Benjamin, Foster, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138251/
https://ncbi.nlm.nih.gov/pubmed/21622984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.249631
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