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Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)
Most genetic changes that promote tumorigenesis involve dysregulation of G1 cell cycle progression. A key regulatory site in G1 is a growth factor–dependent restriction point (R) where cells commit to mitosis. In addition to the growth factor–dependent “R,” which maps to a site about 3.5 hours after...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092273/ https://ncbi.nlm.nih.gov/pubmed/21779436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910392989 |
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