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Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)

Most genetic changes that promote tumorigenesis involve dysregulation of G1 cell cycle progression. A key regulatory site in G1 is a growth factor–dependent restriction point (R) where cells commit to mitosis. In addition to the growth factor–dependent “R,” which maps to a site about 3.5 hours after...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Foster, David A., Yellen, Paige, Xu, Limei, Saqcena, Mahesh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092273/
https://ncbi.nlm.nih.gov/pubmed/21779436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910392989
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