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Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
Flux through metabolic pathways is inherently sensitive to the levels of specific substrates and products, but cellular metabolismis also managed by integrated control mechanisms that sense the nutrient and energy status of a cell or organism. The mechanistic target of rapamycin (mTOR) complex 1 (mT...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743096/ https://ncbi.nlm.nih.gov/pubmed/23728461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2763 |
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