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Nutrient-sensing mTORC1: integration of metabolic and autophagic signals

The ability of adult cardiomyocytes to regenerate is limited, and irreversible loss by cell death plays a crucial role in heart diseases. Autophagy is an evolutionary conserved cellular catabolic process through which long-lived proteins and damaged organelles are targeted for lysosomal degradation....

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Tan, Valerie P., Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909545/
https://ncbi.nlm.nih.gov/pubmed/26773603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.005
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