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Regulation of mTORC1 by PI3K Signaling

The class I phosphoinositide 3-kinase (PI3K) - mechanistic target of rapamycin complex 1 (mTORC1) signaling network directs cellular metabolism and growth. Activation of mTORC1, which is composed of mTOR, Raptor, mLST8, PRAS40, and DEPTOR, depends on the Rag and Rheb GTPases, and requires signals fr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Cell Biol
Prif Awduron: Dibble, Christian C., Cantley, Lewis C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734635/
https://ncbi.nlm.nih.gov/pubmed/26159692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.06.002
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