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Regulation of mTORC1 by PI3K Signaling
The class I phosphoinositide 3-kinase (PI3K) - mechanistic target of rapamycin complex 1 (mTORC1) signaling network directs cellular metabolism and growth. Activation of mTORC1, which is composed of mTOR, Raptor, mLST8, PRAS40, and DEPTOR, depends on the Rag and Rheb GTPases, and requires signals fr...
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| Publicado en: | Trends Cell Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4734635/ https://ncbi.nlm.nih.gov/pubmed/26159692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.06.002 |
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