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Crystal structure of the Rous sarcoma virus intasome

Integration of the reverse-transcribed viral DNA into the host genome is an essential step in the lifecycle of retroviruses. Retrovirus integrase (IN) catalyzes insertions of both ends of the linear viral DNA into a host chromosome (1). IN from HIV-1 and closely related retroviruses share the three-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Yin, Zhiqi, Shi, Ke, Banerjee, Surajit, Pandey, Krishan K., Bera, Sibes, Grandgenett, Duane P., Aihara, Hideki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881392/
https://ncbi.nlm.nih.gov/pubmed/26887497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16950
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