TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin

Regulating the transcription, translation and secretion of cytokines is crucial for controlling the appropriate balance of inflammation. Here we report that the sorting receptor sortilin plays a key role in cytokine production. We observed interactions of sortilin with multiple cytokines including I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Yabe-Wada, Toshiki, Matsuba, Shintaro, Takeda, Kazuya, Sato, Tetsuya, Suyama, Mikita, Ohkawa, Yasuyuki, Takai, Toshiyuki, Shi, Haifeng, Philpott, Caroline C., Nakamura, Akira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879639/
https://ncbi.nlm.nih.gov/pubmed/27220277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26566
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