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PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR

Post‐transcriptional regulation of cytokine production is crucial to ensure appropriate immune responses. We previously demonstrated that poly‐rC‐binding protein‐1 (PCBP1) can act as a trans‐acting factor to stabilize transcripts encoding sortilin, which mediates cytokine trafficking. Here, we repor...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Yabe‐Wada, Toshiki, Philpott, Caroline C., Onai, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050257/
https://ncbi.nlm.nih.gov/pubmed/31961070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12794
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