Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl and asparagyl hyd...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Frey, Avery G., Nandal, Anjali, Park, Jong Hwan, Smith, Pamela M., Yabe, Toshiki, Ryu, Moon-Suhn, Ghosh, Manik C., Lee, Jaekwon, Rouault, Tracey A., Park, Myung Hee, Philpott, Caroline C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050543/
https://ncbi.nlm.nih.gov/pubmed/24843120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402732111
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