A PCBP1–BolA2 chaperone complex delivers iron for cytosolic [2Fe–2S] cluster assembly

Hundreds of cellular proteins require iron (Fe) cofactors for activity, and cells express systems for their assembly and distribution. Molecular details of the cytosolic iron pool used for iron cofactors are lacking, but iron chaperones of the poly rC-binding protein (PCBP) family play a key role in...

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Publicado no:Nat Chem Biol
Main Authors: Patel, Sarju J., Frey, Avery G., Palenchar, Daniel J., Achar, Sooraj, Bullough, Kimberly Z., Vashisht, Ajay, Wohlschlegel, James A., Philpott, Caroline C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702080/
https://ncbi.nlm.nih.gov/pubmed/31406370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0330-6
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