Each Member of the Poly-r(C)-binding Protein 1 (PCBP) Family Exhibits Iron Chaperone Activity toward Ferritin

The mechanisms through which iron-dependent enzymes receive their metal cofactors are largely unknown. Poly r(C)-binding protein 1 (PCBP1) is an iron chaperone for ferritin; both PCBP1 and its paralog PCBP2 are required for iron delivery to the prolyl hydroxylase that regulates HIF1. Here we show th...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Leidgens, Sebastien, Bullough, Kimberly Z., Shi, Haifeng, Li, Fengmin, Shakoury-Elizeh, Minoo, Yabe, Toshiki, Subramanian, Poorna, Hsu, Emory, Natarajan, Navin, Nandal, Anjali, Stemmler, Timothy L., Philpott, Caroline C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682578/
https://ncbi.nlm.nih.gov/pubmed/23640898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460253
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi