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TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin
Regulating the transcription, translation and secretion of cytokines is crucial for controlling the appropriate balance of inflammation. Here we report that the sorting receptor sortilin plays a key role in cytokine production. We observed interactions of sortilin with multiple cytokines including I...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879639/ https://ncbi.nlm.nih.gov/pubmed/27220277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26566 |
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