טוען...

Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington’s disease

Recent studies have identified impairments in neural induction and in striatal and cortical neurogenesis in Huntington’s disease (HD) knock-in mouse models and associated embryonic stem cell lines. However, the potential role of these developmental alterations for HD pathogenesis and progression is...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Molero, Aldrin E., Arteaga-Bracho, Eduardo E., Chen, Christopher H., Gulinello, Maria, Winchester, Michael L., Pichamoorthy, Nandini, Gokhan, Solen, Khodakhah, Kamran, Mehler, Mark F.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878495/
https://ncbi.nlm.nih.gov/pubmed/27140644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603871113
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