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Functions of Huntingtin in Germ Layer Specification and Organogenesis
Huntington’s disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742581/ https://ncbi.nlm.nih.gov/pubmed/23967334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072698 |
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