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Functions of Huntingtin in Germ Layer Specification and Organogenesis

Huntington’s disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored. In...

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Autors principals: Nguyen, Giang D., Molero, Aldrin E., Gokhan, Solen, Mehler, Mark F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742581/
https://ncbi.nlm.nih.gov/pubmed/23967334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072698
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