The Role of H1 Linker Histone Subtypes in Preserving the Fidelity of Elaboration of Mesendodermal and Neuroectodermal Lineages during Embryonic Development

H1 linker histone proteins are essential for the structural and functional integrity of chromatin and for the fidelity of additional epigenetic modifications. Deletion of H1c, H1d and H1e in mice leads to embryonic lethality by mid-gestation with a broad spectrum of developmental alterations. To elu...

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Bibliographic Details
Main Authors: Nguyen, Giang D., Gokhan, Solen, Molero, Aldrin E., Yang, Seung-Min, Kim, Byung-Ju, Skoultchi, Arthur I., Mehler, Mark F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011883/
https://ncbi.nlm.nih.gov/pubmed/24802750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096858
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