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Selective Roles of Normal and Mutant Huntingtin in Neural Induction and Early Neurogenesis
Huntington's disease (HD) is a neurodegenerative disorder caused by abnormal polyglutamine expansion in the amino-terminal end of the huntingtin protein (Htt) and characterized by progressive striatal and cortical pathology. Previous reports have shown that Htt is essential for embryogenesis, a...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653864/ https://ncbi.nlm.nih.gov/pubmed/23691206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064368 |
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