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Functions of Huntingtin in Germ Layer Specification and Organogenesis

Huntington’s disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored. In...

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Detaylı Bibliyografya
Asıl Yazarlar: Nguyen, Giang D., Molero, Aldrin E., Gokhan, Solen, Mehler, Mark F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742581/
https://ncbi.nlm.nih.gov/pubmed/23967334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072698
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