Synthesis and preliminary PET imaging studies of a FAAH radiotracer ([(11)C]MPPO) based on α-ketoheterocyclic scaffold

Fatty acid amide hydrolase (FAAH) is one of the principle enzymes for metabolizing endogenous cannabinoid neurotransmitters such as anandamide, and thus regulates endocannabinoid (eCB) signaling. Selective pharmacological blockade of FAAH has emerged as a potential therapy to discern the endogenous...

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書誌詳細
出版年:ACS Chem Neurosci
主要な著者: Wang, Lu, Yui, Joji, Wang, Qifan, Zhang, Yiding, Mori, Wakana, Shimoda, Yoko, Fujinaga, Masayuki, Kumata, Katsushi, Yamasaki, Tomoteru, Hatori, Akiko, Rotstein, Benjamin H., Collier, Thomas Lee, Ran, Chongzhao, Vasdev, Neil, Zhang, Ming-Rong, Liang, Steven H.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876717/
https://ncbi.nlm.nih.gov/pubmed/26505525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00248
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