Noninvasive quantification of metabotropic glutamate receptor type 1 with [(11)C]ITDM: a small-animal PET study

Because of its role in multiple central nervous system (CNS) pathways, metabotropic glutamate receptor type 1 (mGluR1) is a crucial target in the development of pharmaceuticals for CNS disorders. N-[4-[6-(isopropylamino)-pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[(11)C]-methylbenzamide ([(11)C]IT...

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Hlavní autoři: Yamasaki, Tomoteru, Fujinaga, Masayuki, Yui, Joji, Ikoma, Yoko, Hatori, Akiko, Xie, Lin, Wakizaka, Hidekatsu, Kumata, Katsushi, Nengaki, Nobuki, Kawamura, Kazunori, Zhang, Ming-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982087/
https://ncbi.nlm.nih.gov/pubmed/24398932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.243
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