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PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate

The metabotropic glutamate receptor type 1 (mGluR1) is a novel target protein for the development of new drugs against central nervous system disorders. Recently, we have developed (11)C-labeled PET probes (11)C-ITMM and (11)C-ITDM, which demonstrate similar profiles, for imaging of mGluR1. In the p...

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Detalhes bibliográficos
Main Authors: Yamasaki, Tomoteru, Maeda, Jun, Fujinaga, Masayuki, Nagai, Yuji, Hatori, Akiko, Yui, Joji, Xie, Lin, Nengaki, Nobuki, Zhang, Ming-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999406/
https://ncbi.nlm.nih.gov/pubmed/24795840
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