A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Zahn, Raphael, Osmanović, Dino, Ehret, Severin, Araya Callis, Carolina, Frey, Steffen, Stewart, Murray, You, Changjiang, Görlich, Dirk, Hoogenboom, Bart W, Richter, Ralf P
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Biophysics and Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874776/
https://ncbi.nlm.nih.gov/pubmed/27058170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14119
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