A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zahn, Raphael, Osmanović, Dino, Ehret, Severin, Araya Callis, Carolina, Frey, Steffen, Stewart, Murray, You, Changjiang, Görlich, Dirk, Hoogenboom, Bart W, Richter, Ralf P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874776/
https://ncbi.nlm.nih.gov/pubmed/27058170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14119
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