A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Veröffentlicht in:eLife
Hauptverfasser: Zahn, Raphael, Osmanović, Dino, Ehret, Severin, Araya Callis, Carolina, Frey, Steffen, Stewart, Murray, You, Changjiang, Görlich, Dirk, Hoogenboom, Bart W, Richter, Ralf P
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Biophysics and Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874776/
https://ncbi.nlm.nih.gov/pubmed/27058170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14119
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