A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Zahn, Raphael, Osmanović, Dino, Ehret, Severin, Araya Callis, Carolina, Frey, Steffen, Stewart, Murray, You, Changjiang, Görlich, Dirk, Hoogenboom, Bart W, Richter, Ralf P
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874776/
https://ncbi.nlm.nih.gov/pubmed/27058170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14119
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