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CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis

Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendritic cells (DCs), the key professional antigen pre...

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發表在:Biol Open
Main Authors: Salao, Kanin, Jiang, Lele, Li, Hui, Tsai, Vicky W.-W., Husaini, Yasmin, Curmi, Paul M. G., Brown, Louise J., Brown, David A., Breit, Samuel N.
格式: Artigo
語言:Inglês
出版: The Company of Biologists Ltd 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874360/
https://ncbi.nlm.nih.gov/pubmed/27113959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018119
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