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Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome

Following uptake, Francisella tularensis enters a phagosome that acquires limited amounts of lysosome-associated membrane glycoproteins and does not acquire cathepsin D or markers of secondary lysosomes. With additional time after uptake, F. tularensis disrupts its phagosomal membrane and escapes in...

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Detalhes bibliográficos
Main Authors: Clemens, Daniel L., Lee, Bai-Yu, Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681761/
https://ncbi.nlm.nih.gov/pubmed/19237528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01485-08
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