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Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human Macrophages

Francisella tularensis, the agent of tularemia, is an intracellular pathogen, but little is known about the compartment in which it resides in human macrophages. We have examined the interaction of a recent virulent clinical isolate of F. tularensis subsp. tularensis and the live vaccine strain with...

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Autores principales: Clemens, Daniel L., Lee, Bai-Yu, Horwitz, Marcus A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC415696/
https://ncbi.nlm.nih.gov/pubmed/15155622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3204-3217.2004
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