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Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human Macrophages

Francisella tularensis, the agent of tularemia, is an intracellular pathogen, but little is known about the compartment in which it resides in human macrophages. We have examined the interaction of a recent virulent clinical isolate of F. tularensis subsp. tularensis and the live vaccine strain with...

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Autors principals: Clemens, Daniel L., Lee, Bai-Yu, Horwitz, Marcus A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC415696/
https://ncbi.nlm.nih.gov/pubmed/15155622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3204-3217.2004
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