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Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human Macrophages

Francisella tularensis, the agent of tularemia, is an intracellular pathogen, but little is known about the compartment in which it resides in human macrophages. We have examined the interaction of a recent virulent clinical isolate of F. tularensis subsp. tularensis and the live vaccine strain with...

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Detalhes bibliográficos
Main Authors: Clemens, Daniel L., Lee, Bai-Yu, Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415696/
https://ncbi.nlm.nih.gov/pubmed/15155622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3204-3217.2004
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