The Early Phagosomal Stage of Francisella tularensis Determines Optimal Phagosomal Escape and Francisella Pathogenicity Island Protein Expression

Francisella tularensis is an intracellular pathogen that can survive and replicate within macrophages. Following phagocytosis and transient interactions with the endocytic pathway, F. tularensis rapidly escapes from its original phagosome into the macrophage cytoplasm, where it eventually replicates...

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Bibliographic Details
Main Authors: Chong, Audrey, Wehrly, Tara D., Nair, Vinod, Fischer, Elizabeth R., Barker, Jeffrey R., Klose, Karl E., Celli, Jean
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583578/
https://ncbi.nlm.nih.gov/pubmed/18852245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00682-08
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