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Acquisition of the Vacuolar ATPase Proton Pump and Phagosome Acidification Are Essential for Escape of Francisella tularensis into the Macrophage Cytosol

The Francisella tularensis-containing phagosome (FCP) matures to a late-endosome-like phagosome prior to bacterial escape into the cytosols of macrophages, where bacterial proliferation occurs. Our data show that within the first 15 min after infection of primary human monocyte-derived macrophages (...

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Библиографические подробности
Главные авторы: Santic, Marina, Asare, Rexford, Skrobonja, Ivana, Jones, Snake, Abu Kwaik, Yousef
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423071/
https://ncbi.nlm.nih.gov/pubmed/18390995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00185-08
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