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Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis

Francisella tularensis induces apoptosis within macrophages but the temporal and spatial modulation through activation of caspase-1, caspase-3, and the anti-apoptosis nuclear transcription factor B (NF-κB) is not known. Whether escape of the bacteria into the cytosol is sufficient and/or essential f...

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Bibliographic Details
Main Authors: Santic, Marina, Pavokovic, Gordana, Jones, Snake, Asare, Rexford, Kwaik, Yousef Abu
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819573/
https://ncbi.nlm.nih.gov/pubmed/19925880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2009.11.003
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