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Molecular Complexity Orchestrates Modulation of Phagosome Biogenesis and Escape to the Cytosol of macrophages by Francisella tularensis

Upon entry of Francisella tularensis to macrophages, the Francisella-containing phagosome (FCP) is trafficked into an acidified late endosome-like phagosome with limited fusion to the lysosomes followed by rapid escape into the cytosol where the organism replicates. Although the Francisella Pathogen...

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Detalhes bibliográficos
Main Authors: Asare, Rexford, Kwaik, Yousef Abu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957515/
https://ncbi.nlm.nih.gov/pubmed/20482590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-2920.2010.02229.x
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