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Lack of Fusion of Azurophil Granules with Phagosomes during Phagocytosis of Mycobacterium smegmatis by Human Neutrophils Is Not Actively Controlled by the Bacterium

Biogenesis of phagolysosomes is a very rapid event in neutrophils which takes place with nascent unclosed phagosomes, leading to the release of lysosomal enzymes such as β-glucuronidase in the extracellular medium. We have previously shown that, under nonopsonic conditions, both pathogenic and nonpa...

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Detalhes bibliográficos
Main Authors: Cougoule, Céline, Constant, Patricia, Etienne, Gilles, Daffé, Mamadou, Maridonneau-Parini, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127746/
https://ncbi.nlm.nih.gov/pubmed/11854248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1591-1598.2002
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