CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis

Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendritic cells (DCs), the key professional antigen pre...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Salao, Kanin, Jiang, Lele, Li, Hui, Tsai, Vicky W.-W., Husaini, Yasmin, Curmi, Paul M. G., Brown, Louise J., Brown, David A., Breit, Samuel N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874360/
https://ncbi.nlm.nih.gov/pubmed/27113959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018119
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