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Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

Intracellular chloride channel protein 1 (CLIC1) is a 241 amino acid protein of the glutathione S transferase fold family with redox- and pH-dependent membrane association and chloride ion channel activity. Whilst CLIC proteins are evolutionarily conserved in Metazoa, indicating an important role, l...

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Bibliografiske detaljer
Main Authors: Jiang, Lele, Salao, Kanin, Li, Hui, Rybicka, Joanna M., Yates, Robin M., Luo, Xu Wei, Shi, Xin Xin, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Husaini, Yasmin, Wu, Liyun, Brown, David A., Grewal, Thomas, Brown, Louise J., Curmi, Paul M. G., Breit, Samuel N.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561857/
https://ncbi.nlm.nih.gov/pubmed/22956539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.110072
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