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Novel positive allosteric modulators of GABA(A) receptors with anesthetic activity

GABA(A) receptors are the main inhibitory neurotransmitter receptors in the brain and are targets for numerous clinically important drugs such as benzodiazepines, anxiolytics and anesthetics. We previously identified novel ligands of the classical benzodiazepine binding pocket in α(1)β(2)γ(2) GABA(A...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Maldifassi, Maria C., Baur, Roland, Pierce, David, Nourmahnad, Anahita, Forman, Stuart A., Sigel, Erwin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873749/
https://ncbi.nlm.nih.gov/pubmed/27198062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25943
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