Loading...

α subunits in GABA(A) receptors are dispensable for GABA and diazepam action

The major isoform of the GABA(A) receptor is α(1)β(2)γ(2). The binding sites for the agonist GABA are located at the β(2)+/α(1)− subunit interfaces and the modulatory site for benzodiazepines at α(1)+/γ(2)−. In the absence of α(1) subunits, a receptor was formed that was gated by GABA and modulated...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wongsamitkul, Nisa, Maldifassi, Maria C., Simeone, Xenia, Baur, Roland, Ernst, Margot, Sigel, Erwin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686171/
https://ncbi.nlm.nih.gov/pubmed/29138471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15628-7
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!