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Novel positive allosteric modulators of GABA(A) receptors with anesthetic activity

GABA(A) receptors are the main inhibitory neurotransmitter receptors in the brain and are targets for numerous clinically important drugs such as benzodiazepines, anxiolytics and anesthetics. We previously identified novel ligands of the classical benzodiazepine binding pocket in α(1)β(2)γ(2) GABA(A...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Maldifassi, Maria C., Baur, Roland, Pierce, David, Nourmahnad, Anahita, Forman, Stuart A., Sigel, Erwin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873749/
https://ncbi.nlm.nih.gov/pubmed/27198062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25943
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