A carregar...
Monod-Wyman-Changeux Allosteric Shift Analysis in Mutant α1β3γ2L GABA(A) Receptors Indicates Selectivity and Crosstalk among Intersubunit Transmembrane Anesthetic Sites
Propofol, etomidate, and barbiturate anesthetics are allosteric coagonists at pentameric α1β3γ2 GABA(A) receptors, modulating channel activation via four biochemically established intersubunit transmembrane pockets. Etomidate selectively occupies the two β(+)/α(−) pockets, the barbiturate photolabel...
Na minha lista:
| Publicado no: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399575/ https://ncbi.nlm.nih.gov/pubmed/30696720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.115048 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|