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Comparison of αβδ and αβγ GABA(A) Receptors: Allosteric Modulation and Identification of Subunit Arrangement by Site-Selective General Anesthetics

GABA(A) receptors play a dominant role in mediating inhibition in the mature mammalian brain, and defects of GABAergic neurotransmission contribute to the pathogenesis of a variety of neurological and psychiatric disorders. Two types of GABAergic inhibition have been described: αβγ receptors mediate...

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Détails bibliographiques
Publié dans:Pharmacol Res
Auteurs principaux: Feng, Hua-Jun, Forman, Stuart A.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026480/
https://ncbi.nlm.nih.gov/pubmed/29294355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.12.031
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