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Context-Dependent Modulation of αβγ and αβγ GABA(A) Receptors by Penicillin: Implications for Phasic and Tonic Inhibition

Penicillin, an open-channel blocker of GABA(A) receptors, was recently reported to inhibit phasic, but not tonic, currents in hippocampal neurons. To distinguish between isoform-specific and context-dependent modulation as possible explanations for this selectivity, the effects of penicillin were ev...

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Detalhes bibliográficos
Main Authors: Feng, Hua-Jun, Botzolakis, Emmanuel J., Macdonald, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661208/
https://ncbi.nlm.nih.gov/pubmed/18775733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.08.010
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