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Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: A patch clamp and simulation study
Benzodiazepines (BDZs) are GABA(A) receptor modulators with anxiolytic, hypnotic, and anticonvulsant properties. BDZs are understood to potentiate GABA(A) receptor function by increasing channel opening frequency, in contrast to barbiturates, which increase channel open duration. However, the in vit...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834588/ https://ncbi.nlm.nih.gov/pubmed/19447010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2009.03.007 |
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