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Novel positive allosteric modulators of GABA(A) receptors with anesthetic activity

GABA(A) receptors are the main inhibitory neurotransmitter receptors in the brain and are targets for numerous clinically important drugs such as benzodiazepines, anxiolytics and anesthetics. We previously identified novel ligands of the classical benzodiazepine binding pocket in α(1)β(2)γ(2) GABA(A...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Maldifassi, Maria C., Baur, Roland, Pierce, David, Nourmahnad, Anahita, Forman, Stuart A., Sigel, Erwin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873749/
https://ncbi.nlm.nih.gov/pubmed/27198062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25943
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