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Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord

Dynorphin A is an endogenous opioid peptide derived from the precursor prodynorphin. The proteolytic fragment dynorphin A (1–17) exhibits inhibitory effects via opioid receptors. Paradoxically, the activity of the dynorphin system increases with chronic pain and neuropathy is associated with the up-...

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Podrobná bibliografie
Vydáno v:Neuropharmacology
Hlavní autoři: Bannister, Kirsty, Lee, Yeon Sun, Goncalves, Leonor, Porreca, Frank, Lai, Josephine, Dickenson, Anthony H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873257/
https://ncbi.nlm.nih.gov/pubmed/24937046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.06.005
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