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Spinal Dynorphin and Bradykinin Receptors Maintain Inflammatory Hyperalgesia

An upregulation of the endogenous opioid, dynorphin A, in the spinal cord is seen in multiple experimental models of chronic pain. Recent findings implicate a direct excitatory action of dynorphin A at bradykinin receptors to promote hyperalgesia in nerve injured rats, and its upregulation may promo...

詳細記述

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書誌詳細
主要な著者: Luo, Miaw-Chyi, Chen, Qingmin, Ossipov, Michael H., Rankin, David R., Porreca, Frank, Lai, Josephine
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615572/
https://ncbi.nlm.nih.gov/pubmed/18976961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.06.005
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