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Spinal Dynorphin and Bradykinin Receptors Maintain Inflammatory Hyperalgesia
An upregulation of the endogenous opioid, dynorphin A, in the spinal cord is seen in multiple experimental models of chronic pain. Recent findings implicate a direct excitatory action of dynorphin A at bradykinin receptors to promote hyperalgesia in nerve injured rats, and its upregulation may promo...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615572/ https://ncbi.nlm.nih.gov/pubmed/18976961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.06.005 |
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