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Bayesian Top-Down Protein Sequence Alignment with Inferred Position-Specific Gap Penalties

We describe a Bayesian Markov chain Monte Carlo (MCMC) sampler for protein multiple sequence alignment (MSA) that, as implemented in the program GISMO and applied to large numbers of diverse sequences, is more accurate than the popular MSA programs MUSCLE, MAFFT, Clustal-Ω and Kalign. Features of GI...

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Bibliografische gegevens
Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Neuwald, Andrew F., Altschul, Stephen F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871425/
https://ncbi.nlm.nih.gov/pubmed/27192614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004936
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